i know i know, this site is about land based shark fishing, but i was looking to get some peoples .02 about shark fishing out of boats for monster sharks... We know the basics... Just looking for specifics... Chum or no chum? leader length? water depth? bottom structure?? Please let me know you guys.
There are challenges because it's difficult to leader a shark to the boat with our normal set ups (meaning the long shock leaders). Shorter rod allows for better control next to the boat.
Two different types of fishing. I started out only fishing off my boat and you do allot of stuff differently.
First off is location, you have more of a variety off the boat seeing as you can just change location if no action comes into play. I like either fishing deep drop offs or drifting passes. If you find the right location i would highly recommend using chum. what i always did with my cousin is we would net about 100lbs of mullet and just chunk them or blast them with the 12 gauge 
Another thing you want to consider is tackle, on a boat you can get awat with much much smaller tackle so i would recommend a reel with a lower capacity and higher drag. (i use a avet 50 narrow TRX filled to the top with 200lb jb)
For leaders you dont need any shock mono and i would really advise cable as its much easier to leader the fish when close. I always used 10ft of 660 afw cable to a single or double hooked rig. i would usually float one bait and free line the other.